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AI SkillDesign & UI

proteinmpnn

Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.

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What is this resource?

Design protein sequences using ProteinMPNN inverse folding. Use this skill when: (1) Designing sequences for RFdiffusion backbones, (2) Redesigning existing protein sequences, (3) Fixing specific residues while designing others, (4) Optimizing sequences for expression or stability, (5) Multi-state or negative design. For backbone generation, use rfdiffusion or bindcraft. For ligand-aware design, use ligandmpnn. For solubility optimization, use solublempnn.

Review the original project for installation steps, licenses, compatibility and updates. This directory provides discovery links, not downloadable or verified code.

Installation

For repositories supported by the Skills CLI, you can typically start with:

npx skills add adaptyvbio/protein-design-skills

Check the repository instructions and select the intended skill before installing. This command may not apply to every source.

Safety & attribution

This is an external resource, not independently security-audited by this directory. Inspect permissions, scripts and changes before using it with your files or accounts.